13073_2016_334_MOESM2_ESM.docx (224.36 kB)
Additional file 2: Supplementary figures S1-S5 and supplementary tables S2-S6. of Panx3 links body mass index and tumorigenesis in a genetically heterogeneous mouse model of carcinogen-induced cancer
journal contribution
posted on 2016-08-09, 05:00 authored by Kyle Halliwill, David Quigley, Hio Kang, Reyno Del Rosario, David Ginzinger, Allan BalmainSupplementary figures and supplementary tables S2-S6. A Word (.docx) document containing all supplementary figures and supplementary tables S2-S6. Table S2: Sex interactions by QTL. Difference refers to the difference in means between heterozygous and homozygous mice. Table S3: BMI QTL and papilloma burden. Table S4: Genes significantly associated with BMI. Table S5: Panx3 network gene correlation levels by sex. Table S6: Panx3 polymorphisms between Spret and FVB mice. Figure S1: Twenty-week papilloma burden by BMI for male and female mice. Figure S2: QTL effect for the strongest autosomal QTL for each phenotype by sex for raw and mean-centered phenotype values. Figure S3: Proximal and distal regions of chromosome 10 influence weight in opposing directions. Figure S4: Effect of sex-specific QTL on BMI. Figure S5: Panx3 expression and tumor development. (DOCX 224 kb)