Additional file 2: Figure S2. of VISTA deficiency attenuates antibody-induced arthritis and alters macrophage gene expression in response to simulated immune complexes

showing comparison of splenic gene expression profiles for arthritic and nonarthritic WT versus V-KO mice. RNA isolated from snap-frozen spleens taken from WT (n = 5), V-KO (n = 5), WT CAIA (n = 8), and V-KO CAIA (n = 8) mouse. To examine gene expression, RNA was hybridized on the mouse Immunology NanoString plate and expression was read on an nCounter® Analysis System. Groups compared using limma in R/Bioconductor (see Methods) (JPG 125 kb)