Additional file 2: Figure S2. of The prevalence of ACPA is lower in rheumatoid arthritis patients with an older age of onset but the composition of the ACPA response appears identical

Showing proportion of anti-CarP-negative RA patients at different ages of RA onset; data from two cohorts. Presented are the proportion of anti-CarP-negative and anti-CarP-positive RA patients within the different age groups in the Leiden EAC and BARFOT cohorts. Number of patients in each age group: Leiden EAC: <25, n = 43; 25–29, n = 23; 30–34, n = 44; 35–39, n = 62; 40–44, n = 79; 45–49, n = 111; 50–54, n = 112; 55–59, n = 135; 60–64, n = 144; 65–69, n = 114; 70–74, n = 120; 75–79, n = 87; ≥80, n = 47; BARFOT: <25, n = 18; 25–29, n = 27; 30–34, n = 37; 35–39, n = 41; 40–44, n = 43; 45–49, n = 62; 50–54, n = 96; 55–59, n = 88; 60–64, n = 80; 65–69, n = 103; 70–74, n = 88; 75–79, n = 87; ≥80, n = 38. (TIF 53 kb)