13075_2016_925_MOESM2_ESM.pdf (55.11 kB)
Additional file 2: Figure S2. of Reduced pro-inflammatory profile of γδT cells in pregnant patients with rheumatoid arthritis
journal contribution
posted on 2016-01-22, 05:00 authored by Manuela Tham, Gabriele Schlör, Daniel Yerly, Christina Mueller, Daniel Surbek, Peter Villiger, Frauke FörgerReduced pro-inflammatory cytokine profile of γδT cells in pregnant versus non-pregnant RA patients. Peripheral blood mononuclear cells from healthy women (HC), patients with rheumatoid arthritis (RA), and patients with ankylosing spondylitis (AS) were stained for intracellular cytokines. Mean fluorescence intensity (MFI) of TNFα (A), IFNγ (B), IL-17 (C) and IL-10 (D) among CD3 cells (left panels), Vδ1 cells (middle panels) and Vδ2 cells (right panels) from non-pregnant (np, white boxes) and pregnant women (third trimester, 3T, grey boxes) were analyzed. Box plots show the median and the interquartile ranges. *P < 0.05, **P < 0.01, ***P < 0.001. (PDF 55 kb)