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Additional file 2: Figure S2. of Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal death

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posted on 2017-07-14, 05:00 authored by Arnaud Jacquier, Cécile Delorme, Edwige Belotti, Raoul Juntas-Morales, Guilhem Solé, Odile Dubourg, Marianne Giroux, Claude-Alain Maurage, Valérie Castellani, Adriana Rebelo, Alexander Abrams, Stephan Züchner, Tanya Stojkovic, Laurent Schaeffer, Philippe Latour
eGFP-NEFH WT form filamentous network in vitro and in ovo. A. monomeric eGFP tag NEFH WT expression can form visible filamentous network in SH-EP under lower expression condition when transfected at low concentration (optimal recommended concentration diluted four time). eGFP-NEFH WT form filamentous network in spinal motoneuron in vitro (B) and in vivo (C). Scale bar 10 μm. (TIFF 156 kb)

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