Additional file 2: Figure S1. of The PD-1: PD-L1 pathway promotes development of brain-resident memory T cells following acute viral encephalitis

Decreased expression of CCR7 within the MCMV-infected brain. Mononuclear cells were isolated from the brains of MCMV-infected WT, PD-L1 KO, and PD-1 KO mice at 7 and 30 dpi and used for flow cytometric analysis of CCR7 expression. A. Gating strategy used for analysis of brain-derived leukocytes. B. Representative contour plots show the percentage of brain-infiltrating CD8+ T cells expressing CCR7 at the indicated time points. C. Representative contour plots show the percentage of Ki67+ cells on CD103+ CD8+-gated T cells at 30 dpi. (TIF 238 kb)