Additional file 2: Figure S1. of Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer

ACVR2 interacts with p85 after activin treatment. FET cells were used for co-immunoprecipitation with ACVR2, TGFBR1 or TGFBR2 and Western blotted with p85.  There is an induction of ACVR2/p85 association following activin treatment, however, the increase in ACVR1/p85 association was more pronounced.  Neither TGFBR1 nor TGFBR2 directly associated with p85 following ligand stimulation. (EPS 3051 kb)