Additional file 20: Figure S11. of A multi-omic analysis of human na誰ve CD4+ T cells

Mitchell, Christopher; Getnet, Derese; Kim, Min-Sik; Manda, Srikanth; Kumar, Praveen; Huang, Tai-Chung; Pinto, Sneha; Nirujogi, Raja; Iwasaki, Mio; Shaw, Patrick; Wu, Xinyan; Zhong, Jun; Chaerkady, Raghothama; Marimuthu, Arivusudar; Muthusamy, Babylakshmi; Sahasrabuddhe, Nandini; Raju, Rajesh; Bowman, Caitlyn; Danilova, Ludmila; Cutler, Jevon; Kelkar, Dhanashree; Drake, Charles; Prasad, T.; Marchionni, Luigi; Murakami, Peter; Scott, Alan; Shi, Leming; Thierry-Mieg, Jean; Thierry-Mieg, Danielle; Irizarry, Rafael; Cope, Leslie; Ishihama, Yasushi; Wang, Charles; Gowda, Harsha; Pandey, Akhilesh

doi:10.6084/m9.figshare.c.3602660_D14.v1

12918_2015_225_MOESM20_ESM.pdf (185.78 kB)

Additional file 20: Figure S11. of A multi-omic analysis of human na誰ve CD4+ T cells

journal contribution

posted on 2015-11-06, 05:00 authored by Christopher Mitchell, Derese Getnet, Min-Sik Kim, Srikanth Manda, Praveen Kumar, Tai-Chung Huang, Sneha Pinto, Raja Nirujogi, Mio Iwasaki, Patrick Shaw, Xinyan Wu, Jun Zhong, Raghothama Chaerkady, Arivusudar Marimuthu, Babylakshmi Muthusamy, Nandini Sahasrabuddhe, Rajesh Raju, Caitlyn Bowman, Ludmila Danilova, Jevon Cutler, Dhanashree Kelkar, Charles Drake, T. Prasad, Luigi Marchionni, Peter Murakami, Alan Scott, Leming Shi, Jean Thierry-Mieg, Danielle Thierry-Mieg, Rafael Irizarry, Leslie Cope, Yasushi Ishihama, Charles Wang, Harsha Gowda, Akhilesh Pandey

Correlation of methylation and transcript levels of genes between memory and na誰ve CD4+ T cells. (A) Intersection of promoter methylation and mRNA expression data from na誰ve and memory T cells. Genes marked in red in the upper left quadrant showed significantly reduced expression in na誰ve CD4+ T cells due to promoter hypermethylation. Genes that showed the opposite trend are shown in the bottom right quadrant. (PDF 185 kb)