Additional file 1: of The calibrated model-based concordance improved assessment of discriminative ability in patient clusters of limited sample size

Table S1. Cluster sizes and performance measures across 19 European centers of the CRASH trial. Table S2. Cluster sizes and performance measures at external validation across 36 non-European centers of the CRASH trial. Table S3. Simulation characteristics (2000 replications) of c-index and c-mbc across 40 centers of 200 patients without between center heterogeneity in intercept and slope. Table S4. Simulation characteristics (2000 replications) of c-index and c-mbc across 40 centers of 400 patients. Table S5. Simulation characteristics (2000 replications) of c-index and c-mbc across 40 centers of 200 patients when the regression model was misspecified. Table S6. Simulation characteristics (2000 replications) of c-index and c-mbc across 40 centers of 200 patients when the calibration slopes were not normally distributed. (DOCX 92 kb)