13018_2019_1215_MOESM1_ESM.tif (1.44 MB)

Additional file 1: of Suppression of NLRP3 inflammasome improves alveolar bone defect healing in diabetic rats

Download (1.44 MB)
posted on 30.05.2019 by Hao Li, Xinghua Zhong, Zhiyong Chen, Wei Li
Figure S1. Regulation of alveolar bone defect healing by shRNA targeting NLRP3 under the diabetic condition. a Increased expression of NLRP3 leads to the enhanced expression of ASC and caspase-1, subsequently resulting in the augmented release of proinflammatory cytokine IL-1β and decreased production of osteogenic markers RUNX2 and OCN under the diabetic condition. b shRNA targeting NLRP3 reduces the mRNA level of NLRP3 and inhibits the process shown in Figure S1a. (TIF 1473 kb)


National Natural Science Foundation of China