13058_2017_878_MOESM1_ESM.docx (23.85 kB)
Additional file 1: of Selinexor (KPT-330) demonstrates anti-tumor efficacy in preclinical models of triple-negative breast cancer
journal contribution
posted on 2017-08-15, 05:00 authored by Natalia Arango, Erkan Yuca, Ming Zhao, Kurt Evans, Stephen Scott, Charissa Kim, Ana Gonzalez-Angulo, Filip Janku, Naoto Ueno, Debu Tripathy, Argun Akcakanat, Aung Naing, Funda Meric-BernstamPIK3CA, PTEN, TP53 and Ras/Raf status of cell lines in panel. A panel of breast cancer cell lines was tested with selinexor, and cell growth was measured after 72Â hours of treatment using the SRB assay. IC50 was then calculated using isobologram curves. The mutation statuses for PIK3CA, PTEN, TP53, and Ras/Raf status are reported. (DOCX 23 kb)
