13148_2019_714_MOESM1_ESM.docx (4.04 MB)
Additional file 1: of Replicated methylation changes associated with eczema herpeticum and allergic response
journal contribution
posted on 2019-08-24, 03:52 authored by Meher Boorgula, Margaret Taub, Nicholas Rafaels, Michelle Daya, Monica Campbell, Sameer Chavan, Aniket Shetty, Chris Cheadle, Sangjucta Barkataki, Jinshui Fan, Gloria David, Terri Beaty, Ingo Ruczinski, Jon Hanifin, Lynda Schneider, Richard Gallo, Amy Paller, Lisa Beck, Donald Leung, Rasika Mathias, Kathleen BarnesSupplementary text. Figure S1. QC plot of methylated to unmethylated median intensities for discovery and replication data sets. Figure S2. Plot of chrX vs chrY median intensities to identify gender mismatches for discovery and replication data sets. Figure S3. QQ plots of p values (three phenotype comparisons) from models with seven cell types (top) and six cell types (bottom) prior and post bacon adjustment. Figure S4. QQ plots of p values (severity analysis) from models with seven cell types (top) and six cell types (bottom) prior and post bacon adjustment. Figure S5. Box plots for top 27 CpGs significant in ADEH+ vs controls analysis. Figure S6. Scatter plots of top 27 CpGs significant in eosinophil-methylation analysis showing eosinophil levels against methylation values. Table S1. Clinical Characteristics table for all samples in discovery and replication data sets. Table S10. References to support the selection of genes for our gene-based analysis. (DOCX 4040 kb)
