Springer Nature
Browse
12916_2019_1378_MOESM1_ESM.docx (1.7 MB)

Additional file 1: of RTS,S/AS01E immunization increases antibody responses to vaccine-unrelated Plasmodium falciparum antigens associated with protection against clinical malaria in African children: a case-control study

Download (1.7 MB)
journal contribution
posted on 2019-08-14, 03:58 authored by Carlota DobaĂąo, Itziar Ubillos, Chenjerai Jairoce, Ben Gyan, Marta Vidal, Alfons JimĂŠnez, Rebeca Santano, David Dosoo, Augusto Nhabomba, Aintzane Ayestaran, Ruth Aguilar, Nana Williams, NĂşria DĂ­ez-Padrisa, David Lanar, Virander Chauhan, Chetan Chitnis, Sheetij Dutta, Deepak Gaur, Evelina Angov, Kwaku Asante, Seth Owusu-Agyei, Clarissa Valim, Benoit Gamain, Ross Coppel, David Cavanagh, James Beeson, Joseph Campo, Gemma Moncunill
Supplementary information including figures, tables, methods, results, and references. Figure S1. Antibody responses to non-RTS,S Plasmodium falciparum antigens per visit and vaccination group. Figure S2. Antibody responses to non-RTS,S Plasmodium falciparum antigens after RTS,S/AS01E vaccination stratified by age and site. Figure S3. Association between IgG antibody levels and malaria risk stratified by age and site. Table S1. Antigens included in the multiplex quantitative suspension array panel. Table S2. Effect of RTS,S vaccination and other variables on antibody levels at each study visit by univariable linear regression models. Table S4. Multivariable analysis of the effect of RTS,S/AS01E vaccination and demographic, clinical, and epidemiological variables on antibody levels to Plasmodium falciparum pre-erythrocytic and blood-stage antigens. (DOCX 1736 kb)

Funding

National Institute of Allergy and Infectious Diseases

History