Springer Nature
Browse
13045_2017_462_MOESM1_ESM.xlsx (28.68 kB)

Additional file 1: of Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs

Download (28.68 kB)
dataset
posted on 2017-04-17, 05:00 authored by Todd Knutson, Thu Truong, Shihong Ma, Nicholas Brady, Megan Sullivan, Ganesh Raj, Kathryn Schwertfeger, Carol Lange
Gene sets derived from T47D cells expressing WT PR and KR PR. These gene sets were used in the analysis described in Fig. 5c, d. (A) 16 genes were discovered to be highly upregulated by progestin in cells expressing KR PR, compared to WT PR. These genes were also not regulated by other PR ligands. (B) 101 genes were discovered to be highly upregulated by progestin in cells expressing WT PR, compared to KR PR. These genes were also not regulated by other PR ligands. (XLSX 28 kb)

Funding

National Institutes of Health

History