13058_2019_1153_MOESM1_ESM.pdf (112.54 kB)
Additional file 1: of Leptin produced by obesity-altered adipose stem cells promotes metastasis but not tumorigenesis of triple-negative breast cancer in orthotopic xenograft and patient-derived xenograft models
journal contribution
posted on 2019-05-22, 05:00 authored by Rachel Sabol, Annie Bowles, Alex Côté, Rachel Wise, Benjamen O’Donnell, Margarite Matossian, Fokhrul Hossain, Hope Burks, Luis Valle, Lucio Miele, Bridgette Collins-Burow, Matthew Burow, Bruce BunnellFigure S1. Secreted factors from adipose stem cells promotes proliferation and migration of breast cancer. Conditioned media collected from ASCs after 24 h promotes proliferation of MDA-MB-231, MDA-MB-468, BT20, and HCC1806 TNBC cell lines and TU-BcX-2 K1-derived cells. Values reported are the mean of three independent experiments each performed in triplicate. Bars, ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001. *−obASC vs. control, #−lnASCs vs control (PDF 112 kb)
