Additional file 1: of Improved inference of site-specific positive selection under a generalized parametric codon model when there are multinucleotide mutations and multiple nonsynonymous rates

Dunn, Katherine; Kenney, Toby; Gu, Hong; Bielawski, Joseph

doi:10.6084/m9.figshare.7587662.v1

12862_2018_1326_MOESM1_ESM.pdf (752.36 kB)

Additional file 1: of Improved inference of site-specific positive selection under a generalized parametric codon model when there are multinucleotide mutations and multiple nonsynonymous rates

journal contribution

posted on 2019-01-14, 05:00 authored by Katherine Dunn, Toby Kenney, Hong Gu, Joseph Bielawski

The GPP model uses a logarithm link function to link the non-zero off-diagonal elements of the 61âĂâ61 instantaneous rate matrix to a linear model. (PDF 688 kb)

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Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada

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Codon model Positive selection Protein evolution Multiple nucleotide mutations Multiple nonsynonymous rates M-series models G-series models Likelihood ratio test False positives Model misspecification Codon frequencies

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Additional file 1: of Improved inference of site-specific positive selection under a generalized parametric codon model when there are multinucleotide mutations and multiple nonsynonymous rates

Funding

Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada

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