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Additional file 1: of Impact of obesity on breast cancer recurrence and minimal residual disease

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posted on 2019-03-13, 05:00 authored by Brett Ecker, Jun Lee, Christopher Sterner, Aaron Solomon, Dhruv Pant, Fei Shen, Javier Peraza, Lauren Vaught, Samyukta Mahendra, George Belka, Tien-chi Pan, Kathryn Schmitz, Lewis Chodosh
Figure S1. a Serum glucose levels were measured after an overnight fast at time of clinical recurrence (n = 50/arm). Fasting glucose levels were elevated in HFD-Obese mice relative to HFD-Lean and LFD mice (129.8 ± 33.2 mg/dl vs. 118.9 ± 15.6 mg/dl vs. 114.7 ± 18.7 mg/dl, respectively; p < 0.001). b Glucose values during 2-h intraperitoneal glucose tolerance test (IP-GTT). c Quantification of 2-h IP-GTT using AUCglucose, where HFD-Obese mice had significantly higher glucose levels relative to HFD-Lean and LFD mice (23,341.7.4 ± 9202.8 mg/dl/minute vs. 17,331.2 ± 6227.8 mg/dl/minute vs. 16,747.8 ± 8681.4 mg/dl/minute, respectively; p < 0.001; n = 50/arm). Error bars represent the SEM. *p < 0.05, **p < 0.01, and ***p < 0.001. (TIFF 837 kb)

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National Cancer Institute (US)

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