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Additional file 1: of Fast self-navigated wall shear stress measurements in the murine aortic arch using radial 4D-phase contrast cardiovascular magnetic resonance at 17.6 T

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posted on 2019-10-15, 05:48 authored by Patrick Winter, Kristina Andelovic, Thomas Kampf, Fabian Gutjahr, Julius Heidenreich, Alma Zernecke, Wolfgang Bauer, Peter Jakob, Volker Herold
Figure S1–S3. Reproducibility of the measurement method, tested in three different mice at two measurement days (time between two measurement days: 7 days). Correlation and Bland-Altman Plots were generated for all relevant parameters. In particular for the longitudinal and circumferential WSS values, a good reproducibility can be observed. Deviations between both measurements are mainly caused by differences in slice positioning, uncertainties in calculating the centerline and segmentation as well as off-resonance effects. Figure S4–S6. Stability of the measurement method, assessed by reconstructing one dataset using varying numbers of subsets (n = 1, 2, . . ., 10) for reconstruction. The largest deviation (relative to the 10-subsets-reconstruction) was found, when less than 6 subsets were used for reconstruction. To assess the error within a measurement, 5 reconstructions were generated using different ensembles of subsets (reconstruction 1: subsets 1–6. reconstruction 2: subsets 2–7. reconstruction 3: subsets 3–8. reconstruction 4: subsets 4–9. reconstruction 5: subsets 5–10). Mean values and standard deviations were determined over all 5 datasets for 12 regions of interests. For the longitudinal WSS, a mean standard deviation of approx. 7.5% was estimated. (PDF 16066 kb)

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