Additional file 1: of Evidence supporting regulatory-decision making on orphan medicinal products authorisation in Europe: methodological uncertainties

Table S1. Characteristics used to describe the evidence supporting marketing authorization application in European Public Assessment Reports of Orphan Medicinal Products. Table S2. Clustering of the 85 medical conditions in European Public Assessment Reports of Orphan Medicinal Products. Table S3. Dictionary of some methodological terms. Figure S1. Number of European Public Assessment Reports in each cluster. (DOCX 47 kb)