Additional file 1: of Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes

Castro, Andrea; Ozturk, Kivilcim; Pyke, Rachel; Xian, Su; Zanetti, Maurizio; Carter, Hannah

doi:10.6084/m9.figshare.9109199.v1

12920_2019_544_MOESM1_ESM.pdf (1.29 MB)

Additional file 1: of Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes

journal contribution

posted on 2019-07-26, 04:24 authored by Andrea Castro, Kivilcim Ozturk, Rachel Pyke, Su Xian, Maurizio Zanetti, Hannah Carter

Figure S1. MHC-I complex 3D structure.Â 3D crystal structure of MHC-I complex is displayed as B2M/HLA-A complex (PDB: 3bo8). Interface (blue and violet) and core (green and orange) regions of B2M and HLA-A proteins are highlighted, respectively. Transparent blue and violet regions correspond to the surface regions of B2M and HLA-A proteins, respectively. (PDF 1324 kb)