Springer Nature
Browse
12989_2017_227_MOESM1_ESM.docx (1.04 MB)

Additional file 1: of Effects of urban coarse particles inhalation on oxidative and inflammatory parameters in the mouse lung and colon

Download (1.04 MB)
journal contribution
posted on 2017-11-22, 05:00 authored by Cécile Vignal, Muriel Pichavant, Laurent Alleman, Madjid Djouina, Florian Dingreville, Esperanza Perdrix, Christophe Waxin, Adil Ouali Alami, Corinne Gower-Rousseau, Pierre Desreumaux, Mathilde Body-Malapel
Figure S1. Location of the sampling site. Figure S2. Meteorological conditions during the sampling period. A Temperature. B Relative humidity. C Rain. D Wind speed. E Wind direction and frequency. Figure S3. Comparison of trace element concentrations in cPMD collected at Douai and coarse PM collected in Helsinki, Finland [30] and Budapest, Hungary [31]. Figure S4. Effects of NAC in the basal condition. All mice inhaled sterile water. Mice that received NAC (15 μg/kg/day for 14 days) in drinking water were compared with CT mice that did not receive NAC in drinking water. A Serum MDA levels. B iNKT cell count measured by flow cytometry. C Quantitative PCR (qPCR) analysis of cytokine and chemokine mRNA levels in the lung. D qPCR analysis of mRNA levels of oxidative stress markers in the lung. E MPO activity in the colon. F qPCR analysis of cytokine and chemokine mRNA levels in the colon. Data are presented as mean ± SEM. *p < 0.05, Mann-Whitney U test. (DOCX 1064 kb)

Funding

Hauts-de-France Region

History