Additional file 1: of Development of metabolic and inflammatory mediator biomarker phenotyping for early diagnosis and triage of pediatric sepsis

Supplemental descriptions of methods, statistical modeling, results of subgroups, discussion of the importance of the metabolites and protein mediators of interest (biomarkers) identified, and supplemental references. This file also includes two tables. Table E1. The metabolites (non-targeted 1H NMR spectroscopy and metabolite concentration profiling) and protein mediators (targeted bead-based multiplex assay) detected and quantified. Table E2. Comparison of statistical measures calculated for the supervised OPLS-DA models without excluding outliers from the results presented in the main text of the article. (PDF 307 kb)