Additional file 1: of BET protein inhibition regulates cytokine production and promotes neuroprotection after spinal cord injury

JQ1 treatment modifies the M1 marker INOS but do not modify markers of M2 macrophage phenotype, or astrocyte reactivity. Real-time PCR quantification of (A) M1 and M2 markers and (B) macrophage and glial markers at 4 and 72 h after SCI, normalized to the GAPDH levels. N =3-4 mice/group. *p < 0.05, ***p < 0.005, as calculated by one-way ANOVA followed by Tukey post-hoc test. Data are represented as mean ± SEM fold changes of gene expression. (TIF 1771 kb)