Additional file 1 of Analyses of key genes involved in Arctic adaptation in polar bears suggest selection on both standing variation and de novo mutations played an important role

Additional file 1: Supplementary Table S1. Phenotypes associated with the genes of interest. Phenotype information taken from GeneCards ( genecards.org ). * UniProtKB/Swiss-Prot summary as the associated phenotypes are not available on Genecards. Supplementary Table S5: Genbank accession codes for the polar bear, giant panda (annotation version 102*), and human transcript sequences used in the study. *Available from: https://ftp.ncbi.nlm.nih.gov/genomes/all/annotation_releases/9646/102/ . Supplementary Fig. 1: Principal component analysis of ABCC6 and the 50 kb flanking regions using all individuals included in this study. Supplementary Fig. 2: Principal component analysis of AIM1 and the 50 kb flanking regions using all individuals included in this study. Supplementary Fig. 3: Principal component analysis of APOB and the 50 kb flanking regions using all individuals included in this study. Supplementary Fig. 4: Principal component analysis of COL5A and the 50 kb flanking regions using all individuals included in this study. Supplementary Fig. 5: Principal component analysis of CUL7 and the 50 kb flanking regions using all individuals included in this study. Supplementary Fig. 6: Principal component analysis of EHD3 and the 50 kb flanking regions using all individuals included in this study. Supplementary Fig. 7: Principal component analysis of FCGBP and the 50 kb flanking regions using all individuals included in this study. Supplementary Fig. 8: Principal component analysis of LAMC3 and the 50 kb flanking regions using all individuals included in this study. Supplementary Fig. 9: Principal component analysis of LYST and the 50 kb flanking regions using all individuals included in this study. Supplementary Fig. 10: Principal component analysis of POLR1A and the 50 kb flanking regions using all individuals included in this study. Supplementary Fig. 11: Principal component analysis of TTN and the 50 kb flanking regions using all individuals included in this study. Supplementary Fig. 12: Principal component analysis of XIRP1 and the 50 kb flanking regions using all individuals included in this study.