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Additional file 1: of Allogenic Vγ9Vδ2 T cell as new potential immunotherapy drug for solid tumor: a case study for cholangiocarcinoma

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posted on 2019-02-08, 05:00 authored by Mohammed Alnaggar, Yan Xu, Jingxia Li, Junyi He, Jibing Chen, Man Li, Qingling Wu, Li Lin, Yingqing Liang, Xiaohua Wang, Jiawei Li, Yi Hu, Yan Chen, Kecheng Xu, Yangzhe Wu, Zhinan Yin
Figure S1. Purity of infused allogenic Vγ9Vδ2 T cells of all 8 treatment courses is > 85%. According to flow cytometry data, rest non Vδ2 T cells including Vδ1 T cells, NK cells, B cells, NKT cells, CD8+T cells, CD4+T cells, CD4+CD8+T cells, and CD4-CD8-T cells. Figure S2. Molecular phenotypes of allogenic Vγ9Vδ2 T cells cultured using our developed specific culture formula, showing high expression of killing related molecules (like NKG2D, IFN-γ, TNF-α, CD107a) and low expression of inhibitory molecules like PD-1. (PPTX 255 kb)

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