Additional file 1: Table S1. of The association of diabetes mellitus and insulin treatment with expression of insulin-related proteins in breast tumors

Antibodies used for immunohistochemical assays. Table S2 Overview of the number of positively stained and unevaluable immunohistochemical markers; with for the evaluable cores the median percent of tumor cells with moderate to strong protein expression. Table S3. Average Body Mass Index of breast cancer patients in subgroups of menopausal status, in the ten imputed datasets (% (n)). Table S4. Characteristics of breast cancer patients with and without diabetes and of insulin and non-insulin users. Table S5. Patient characteristics and medication use among women with type 1 and type 2 diabetes. Table S6. Numbers and proportions of tumor protein expression status of women with diabetes, type 2 diabetes and without diabetes in all women and in subgroups of menopausal status. Table S7. Odds ratios for tumor protein expression status of women with type 2 diabetes compared to women without diabetes, and of women with and without diabetes in subgroups of menopausal status. Table S8. Number and proportion of tumor protein expression status of women with type 1 and type 2 diabetes treated with insulin (human and analogues) and without insulin. Table S9. Number and proportion of tumor protein expression status of women with diabetes treated with insulin and without insulin in subgroups of menopausal status and ER tumor status. Table S10. Odds ratios for tumor protein expression status of women with diabetes; treated with insulin analogues compared to women treated with human insulin; type 1 compared to type 2 insulin users; treated with insulin compared to women not treated with insulin in subgroups of menopausal status and in subgroups of ER tumor status. (DOCX 88 kb)