Additional file 1: Table S1. of Metabolic status of CSF distinguishes rats with tauopathy from controls

Abbreviations of metabolites used in targeted metabolomic analysis. Tables S2, S3. Results of analysis of CSF from confirmatory study: targeted analysis (Table S2) and untargeted (Table S3). Table S4. Twenty most discriminating features from untargeted analysis of brain tissue samples. Figure S1. Expression levels of insoluble tau proteins in brainstem of transgenic animals used for study. Figures S2, S3, S4, S5, S6, S7. OPLS-DA score scatterplots and S-plots built for targeted and untargeted metabolomics: CSF targeted (Fig. S2) and untargeted (Fig. S5) metabolomics, plasma targeted (Fig. S3) and untargeted (Fig. S6) metabolomics, brain tissue targeted (Fig. S4) and untargeted (Fig. S7) metabolomics. Figures S8, S9. OPLS-DA score scatterplots and S-plots built for targeted and untargeted metabolomics of CSF in confirmation study: targeted (Fig. S8) and untargeted (Fig. S9) metabolomics. Figure S10. Box plots of most discriminating features of brain tissue samples in untargeted metabolomic analysis. (DOCX 4660 kb)