Additional file 1: Figure S1. of The kinase inhibitor D11 induces caspase-mediated cell death in cancer cells resistant to chemotherapeutic treatment

Viability analysis of U-87 MG cells. Cells were treated with variable concentrations of D11 for the indicated times. The proportion of viable cells is expressed in arbitrary units as a difference in absorbance measured at 450 nm and 690 nm (reference) wavelengths, respectively. Control cells were incubated with vehicle (0.1 % DMSO). Asterisks denote statistical significant differences between control, 25 μM and 50 μM D11-treated cells for each time point, respectively, (N = 6, *, P <0.0001). (JPEG 30 kb)