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Additional file 1: Figure S1. of Sublethal dose of irradiation enhances invasion of malignant glioma cells through p53-MMP 2 pathway in U87MG mouse brain tumor model

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posted on 2015-08-06, 05:00 authored by Jian Pei, In-Ho Park, Hyang-Hwa Ryu, Song-Yuan Li, Chun-Hao Li, Sa-Hoe Lim, Min Wen, Woo-Youl Jang, Shin Jung
The illustration of the experimental process to assess radiation effect on brain tumor in vivo. After implantation U87-Fluc cells into brain, tumor bioluminescence of mouse brain bearing U87-Fluc was continuously observed from day 10 to 28 using the IVIS 100 imaging system. Radiation was exposed to either Single dose 6Gy or 2Gy fractions 5 times for 7 days on 14 day after U87-Fluc implantation. Mice brain were performed with Hematoxylin and eosin or immunohistochemical staining after execution on 30 day. (PPTX 381 kb)

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