13293_2016_57_MOESM1_ESM.ppt (182.5 kB)
Additional file 1: Figure S1. of Low expression of estrogen receptor β in T lymphocytes and high serum levels of anti-estrogen receptor α antibodies impact disease activity in female patients with systemic lupus erythematosus
presentation
posted on 2016-01-12, 05:00 authored by Angela Maselli, Fabrizio Conti, Cristiano Alessandri, Tania Colasanti, Cristiana Barbati, Marta Vomero, Laura Ciarlo, Mario Patrizio, Francesca Spinelli, Elena Ortona, Guido Valesini, Marina PierdominiciERα and ERβ Western blot analysis of T-cell lysates from SLE patients and healthy controls. The expression of ERα and ERβ was evaluated in T lymphocytes from SLE patients, divided in patients with SLEDAI-2K scores <6 and ≥6 and healthy controls (n = 5 subjects for group). A Data from representative subjects are shown. B Densitometry analysis of protein levels relative to GAPDH is also shown. Values are expressed as mean ± SD. Statistical differences were calculated by the Mann-Whitney U test. *p < 0.001 versus healthy controls and patients with SLEDAI-2K scores <6. Ctrs, healthy controls. (PPT 182 kb)
