Additional file 1: Figure S1. of Low expression of estrogen receptor β in T lymphocytes and high serum levels of anti-estrogen receptor α antibodies impact disease activity in female patients with systemic lupus erythematosus

ERα and ERβ Western blot analysis of T-cell lysates from SLE patients and healthy controls. The expression of ERα and ERβ was evaluated in T lymphocytes from SLE patients, divided in patients with SLEDAI-2K scores <6 and ≥6 and healthy controls (n = 5 subjects for group). A Data from representative subjects are shown. B Densitometry analysis of protein levels relative to GAPDH is also shown. Values are expressed as mean ± SD. Statistical differences were calculated by the Mann-Whitney U test. *p < 0.001 versus healthy controls and patients with SLEDAI-2K scores <6. Ctrs, healthy controls. (PPT 182 kb)