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Additional file 1: Figure S1. of Knockdown of NAT12/NAA30 reduces tumorigenic features of glioblastoma-initiating cells
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posted on 2015-08-21, 05:00 authored by Awais Mughal, Zanina Grieg, HĂĽvard Skjellegrind, Artem Fayzullin, Mustapha Lamkhannat, Mrinal Joel, M. Ahmed, Wayne Murrell, Einar Vik-Mo, Iver Langmoen, Biljana StangelandMicroarray analysis of the selected NAT genes. A, Expression of NAA30/NAT12 in tissues and cells. Expression was measured by microarray analysis of 17 cell cultures (NSCs, NFCs and GICs) and four tissue specimens from normal and GBM tissues. Median expression in cell cultures was 126.8 while in tissues it was 94.29 with p value of 0.0013. B-H, Expression of the selected NATs in NSCs, GICs, normal brain tissues, GBM and NFCs. P values were calculated using the Mann Whitney test. Due to small sample sizes the p values proved reliable only for GICs vs. NSCs and were as follows: p(NAT12)=0.023, p(NAT6)=0.0002, p(NAT14)=0.78, p(NAT13)=0.3231, p(NAT8L)=0.0057, p(NAT8)=0.0006, p(NAT8B)=0.003 and p(NAT10)=0.4331.
