12974_2016_596_MOESM1_ESM.tif (41.41 MB)
Additional file 1: Figure S1. of IL4 induces IL6-producing M2 macrophages associated to inhibition of neuroinflammation in vitro and in vivo
figure
posted on 2016-06-07, 05:00 authored by Giacomo Casella, Livia Garzetti, Alberto Gatta, Annamaria Finardi, Chiara Maiorino, Francesca Ruffini, Gianvito Martino, Luca Muzio, Roberto FurlanGene expression of typical M1 and M2 markers in peritoneal macrophages stimulated in vitro. (A–D) real-time RT-PCR for iNOS, Ym1, CCI17, and iL6, in non stimulated (NS), and in macrophages stimulated with different doses of iFn-γ (m1) and iL4 (M2). Gapdh has been used as a housekeeping gene. Data are shown as fold induction (Fi ± standard deviation) over NS. (TIF 42402 kb)