Additional file 1: Figure S1. of IL-1β mediates lung neutrophilia and IL-33 expression in a mouse model of viral-induced asthma exacerbation

IL-1β mRNA expression induced at exacerbation in the WT mice while completely abolished in both IL-1β−/− groups. mRNA was measured from lung tissue homogenates by RT-qPCR. The relative gene expression was related to the reference gene 18S and normalised to control. Data are presented as mean ± SEM, n = 4–7 mice in each group. ## = p < 0.01 compared to respective HDM/Saline control and comparison between WT and IL-1β−/−, at exacerbation is indicated by ** = p < 0.01. (TIFF 542 kb)