Additional file 1: Figure S1. of Amyloid β-protein oligomers upregulate the β-secretase, BACE1, through a post-translational mechanism involving its altered subcellular distribution in neurons

Double immunofluorescence staining with BACE1 and APP antibodies. Primary cortical neurons were treated with 2.5 μM Aβ-O or vehicle for 3 days, followed by double immunofluorescence staining with anti-BACE1 and anti-APP antibodies. Scale bar = 20 μm. (PDF 384 kb)