Additional file 1: Figure S1. of Amplification and propagation of interleukin-1β signaling by murine brain endothelial and glial cells

Primary mixed glia and enriched astrocyte response to IL-1β is MyD88-dependent. Inflammatory gene expression in A. Primary mixed glia and B. Enriched astrocyte cultures from WT and MyD88KO mice that were treated with PBS or IL-1β (50 ng/mL) for 4 h. n = 4 per group. Data are expressed as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001 vs. WT PBS group, #p < 0.001 vs. WT IL-1β group. (PDF 474 kb)