Additional file 1: Figure S1. of All-trans retinoic acid synergizes with topotecan to suppress AML cells via promoting RARα-mediated DNA damage

The TPT effect compared with doxorubicin (ADR). TPT induced cytotoxicity was Compared with ADR in AML cells. 4 × 103 cells per well were cultured in 96-well plates and incubated with the indicated concentrations of TPT and ADR for 48 h. Mean ± SD from three independent experiments. (TIF 10371 kb)