Additional file 1: Figure S1. of Adult muscle-derived stem cells engraft and differentiate into insulin-expressing cells in pancreatic islets of diabetic mice

Schematic representation of the MIP-eGFP and RIP-mCherry transgenic reporter mice. Two transgenic mouse reporter models were used. The first, MIP-eGFP, contains a reporter element expressing eGFP under the control of the mouse INS1 promoter. The second, RIP-mCherry, contains monomeric mCherry under the control of the rat INS2 gene promoter. Both constructs express eGFP or mCherry in vivo exclusively in insulin-expressing beta cells in the pancreas. (JPG 150 kb)