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Additional file 1: Figure S1. of A critical time window for the analgesic effect of central histamine in the partial sciatic ligation model of neuropathic pain

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posted on 2016-06-24, 05:00 authored by Jie Yu, Ying-Ying Tang, Ran-Ran Wang, Guo-Dong Lou, Ting-Ting Hu, Wei-Wei Hou, Jia-Xing Yue, Hiroshi Ohtsu, Li-Yun Shi, Shi-Hong Zhang, Zhong Chen
Effects of histidine administered in other regimens on mechanical allodynia (A) and thermal hyperalgesia (B) following PSL in rats. Histidine (100 mg/kg, i.p.) or saline was administered once daily during the period of 0–14 days PO, 0–7 days PO, or 8–14 days PO. *P < 0.05, **P < 0.01, and ***P < 0.001, compared with the saline-treated group. # P < 0.05, ## P < 0.01, compared with the baseline. n = 7–9/group. (TIF 1,201 kb)

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