Additional file 18: of Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance

Psoriasis-specific and non-specific DEGPs show divergent responses in KCs following gene perturbations and in mouse skin phenotypes. Analyses shown in Figs. 6 and 7 were repeated with respect to KC gene perturbations (a) (65 lists; *HaCaT; **reconstituted epidermis; “ + ” denotes overexpression of a gene rather than RNA interference knockdown) and laboratory mouse phenotypes (b) (35 lists). For each ordered gene list set, the sliding window approach was used to identify the ten lists with the strongest enrichment differences between psoriasis-specific DEGPs and non-specific DEGPs (see Figs. 6 and 7 legends). (TIFF 2368 kb)