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Additional file 17: Table S8. of Evaluation of logistic regression models and effect of covariates for case–control study in RNA-Seq analysis

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posted on 2017-02-06, 05:00 authored by Seung Choi, Adam Labadorf, Richard Myers, Kathryn Lunetta, Josée Dupuis, Anita DeStefano
Type-I error rates of the NB regression from the balanced design with N D=1  = 10, μ D=0  = 1000, and log2fc = 0.3. Disp: Dispersion, CovOR: Odds ratios between covariates and case–control status, Ncov: The number of covariates in a model, NB: Negative binomial regression, MLD: Maximum likelihood estimated Dispersion, QLD: Quasi-likelihood estimated Dispersion, TD: The dispersion is used for the sampling. (DOCX 59 kb)

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National Institute of Diabetes and Digestive and Kidney Diseases

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    BMC Bioinformatics

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    RNA-Sequencing analysisFirth’s logistic regressionNegative binomial regressionCovariate effect

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