Additional file 16: Figure S8. of Telomere heterogeneity linked to metabolism and pluripotency state revealed by simultaneous analysis of telomere length and RNA-seq in the same human embryonic stem cell

Heat-map showing expression of marker genes for human naïve ESCs. Of the 12 selected genes related to pluripotency, genes for naïve pluripotency, NANOG, KLF2, KLF4, TBX3, DPPA3 (STELLA), DPPA5, PRDM14, ESRRB, and REX1 are expressed at high levels in human naïve ESCs, whereas OTX2, ZIC2, ZIC3, and FGF5 decreased in human naïve ESCs. The vertical color scale is shown as log(TPM + 1). (PDF 1132 kb)