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Additional file 15: of A gene expression assay for simultaneous measurement of microsatellite instability and anti-tumor immune activity
figure
posted on 2019-01-21, 05:00 authored by Patrick Danaher, Sarah Warren, SuFey Ong, Nathan Elliott, Alessandra Cesano, Sean FerreeMicrosatellite instability (MSI) predictor signature plotted against Tumor Inflammation Signature (TIS) across histological subtypes of TCGA STAD dataset. Each panel shows a distinct histological subtype of TCGA STAD dataset. Color denotes high-level microsatellite instability (MSI-H) vs. microsatellite stable (MSS) tumors as determined by conventional tests. Lines show cutoffs for each assay: the MSI Predictor score threshold corresponds to a p-value cutoff of 0.01, and the TIS score threshold is set at a level recommended by Danaher et al. 2018. (TIFF 24700 kb)