Additional file 15: of A gene expression assay for simultaneous measurement of microsatellite instability and anti-tumor immune activity

Microsatellite instability (MSI) predictor signature plotted against Tumor Inflammation Signature (TIS) across histological subtypes of TCGA STAD dataset. Each panel shows a distinct histological subtype of TCGA STAD dataset. Color denotes high-level microsatellite instability (MSI-H) vs. microsatellite stable (MSS) tumors as determined by conventional tests. Lines show cutoffs for each assay: the MSI Predictor score threshold corresponds to a p-value cutoff of 0.01, and the TIS score threshold is set at a level recommended by Danaher et al. 2018. (TIFF 24700 kb)