Additional file 14: of Transcriptional factor six2 promotes the competitive endogenous RNA network between CYP4Z1 and pseudogene CYP4Z2P responsible for maintaining the stemness of breast cancer cells

Figure S8. Proposed model in which transcriptional factor six2-mediated regulation of ceRNET_CC is responsible for breast CSC formation and thus drug resistance. Transcriptional factor six2 induces the progression of ceRNET_CC by directly binding to the promoters of CYP4Z1 and the pseudogene CYP4Z2P. This six2/ceRNET_CC regulatory axis results in breast CSC progression and thus enhances drug sensitivity. (TIF 242 kb)