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Additional file 14: of Important cardiac transcription factor genes are accompanied by bidirectional long non-coding RNAs

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posted on 2018-12-27, 05:00 authored by Yutaro Hori, Yoko Tanimoto, Satoru Takahashi, Tetsushi Furukawa, Kazuko Koshiba-Takeuchi, Jun Takeuchi
In situ hybridization of Tbx5 and Nppa in WT and KD chimeric mice at E9.5. The expression pattern of Tbx5 at the mRNA level appeared to be not changed. KD embryos showed an ectopic expression of Nppa around the pre-ventricular septal region, which is frequently observed among embryos with abnormal development of ventricular septum. (PNG 6143 kb)

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Japan Society for the Promotion of Science

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    BMC Genomics

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    Heart developmentLong non-coding RNAHaploinsufficiencyBidirectional promoter

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