Additional file 14: Figure S8. of Cleavage modification did not alter blastomere fates during bryozoan evolution

4D recordings of M. membranacea embryos treated with the MEK inhibitor U0126. Each row corresponds to the timeline of an individual embryo. All recordings were synchronized by the timing of the second cleavage (4-cell stage = 0 h). Time scale shows the number of hours after 4-cell stage. The exact developmental time is shown on panels that do not correspond to the time shown in the main scale (top right corner). Frame number of each panel is shown on the bottom left corner (a frame was captured every 40 s). The orange rectangle indicates the cleavage abnormality observed in embryos that exhibit the severe phenotype. (PNG 6748 kb)