Additional file 13: Figure S5. of An integrative genome-wide transcriptome reveals that candesartan is neuroprotective and a candidate therapeutic for Alzheimer’s disease

Pathways associated with genes preferentially expressed in neurons. Figure S5 notes pathways that are downregulated in Alzheimer’s disease and upregulated by candesartan in our neuronal cultures. Genes are in green in the outer circle and pathways are in orange (activated) or blue (inhibited) in the inside circle. Orange dotted lines are for positive effect and blue dotted lines are for negative effect of the gene on the pathway. (PDF 892 kb)