13195_2015_167_MOESM13_ESM.pdf (892.02 kB)
Additional file 13: Figure S5. of An integrative genome-wide transcriptome reveals that candesartan is neuroprotective and a candidate therapeutic for Alzheimerâs disease
journal contribution
posted on 2016-01-28, 05:00 authored by Abdel Elkahloun, Roman Hafko, Juan SaavedraPathways associated with genes preferentially expressed in neurons. Figure S5 notes pathways that are downregulated in Alzheimerâs disease and upregulated by candesartan in our neuronal cultures. Genes are in green in the outer circle and pathways are in orange (activated) or blue (inhibited) in the inside circle. Orange dotted lines are for positive effect and blue dotted lines are for negative effect of the gene on the pathway. (PDF 892 kb)