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Additional file 12: of Incorporating individual historical controls and aggregate treatment effect estimates into a Bayesian survival trial: a simulation study

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posted on 2019-04-24, 05:00 authored by Caroline Brard, Lisa Hampson, Nathalie Gaspar, Marie-Cécile Le Deley, Gwénaël Le Teuff
Tables A13-A16. Impact of α0 and ω on the operating characteristics for scenarios S25 to S32 when there is a conflict in terms of the underlying survival distribution between historical and new data. These tables describe the impact of α0 and ω on the operating characteristics in case of a conflict in terms of survival distribution between historical and new data. Tables A13 and A14 describe results for scenarios S25 to S28 when the historical data follow a Weibull distribution, the new data follow a piecewise exponential distribution, and data are analysed using either a Bayesian Weibull model (Table A13) or a Bayesian piecewise exponential model (Table A14). Tables A15 and A16 describe results for scenarios S29 to S32 when the historical data follow a piecewise exponential distribution, the new data follow a Weibull distribution, and data are analysed using either a Bayesian piecewise exponential model (Table A15) or a Bayesian Weibull model (Table A16). (PDF 554 kb)

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