13046_2018_683_MOESM11_ESM.pdf (162.43 kB)
Additional file 11: of TFAP2C promotes stemness and chemotherapeutic resistance in colorectal cancer via inactivating hippo signaling pathway
journal contribution
posted on 2018-02-13, 05:00 authored by Xu Wang, Di Sun, Jiandong Tai, Si Chen, Miao Yu, Dong Ren, Lei WangFigure S6. (A) Activity of luciferase reporter constructs of several signaling pathway were examined in the TFAP2C-overexpressing or âsilencing CRC cells. (B and C) TFAP2C expression level was positively associated with the YAP and TAZ-activated gene signatures. (D-G) TFAP2C expression level is positively associated with the protein expression levels of transcriptional co-activators YAP and TAZ of Hippo signaling pathway as assessed through CRC dataset from TCGA. (PDF 162Â kb)