Additional file 11: of TFAP2C promotes stemness and chemotherapeutic resistance in colorectal cancer via inactivating hippo signaling pathway

Figure S6. (A) Activity of luciferase reporter constructs of several signaling pathway were examined in the TFAP2C-overexpressing or –silencing CRC cells. (B and C) TFAP2C expression level was positively associated with the YAP and TAZ-activated gene signatures. (D-G) TFAP2C expression level is positively associated with the protein expression levels of transcriptional co-activators YAP and TAZ of Hippo signaling pathway as assessed through CRC dataset from TCGA. (PDF 162 kb)