Additional file 11: Figure S5. of Single-cell analysis of long non-coding RNAs in the developing human neocortex

Expression of lncRNAs and mRNAs in single cells and whole tissues. A Distributions of non-zero lncRNA (blue) and mRNA (red) expression in 276 single cells from neocortex. The median lncRNA expression and the median mRNA expression for each cell was compared as a ratio and summarized in Fig. 3b. B Distributions of non-zero lncRNA (blue) and mRNA (red) expression in eight bulk tissue RNA-seq samples using the same set of 1400 lncRNAs and 10929 mRNAs as in (A). C Distributions of non-zero lncRNA (blue) and mRNA (red) expression in in silico merged neocortex single cells. D Proportion of single neocortex cells that expressed each lncRNA (blue) and mRNA (red), binned by their expression levels in bulk tissues. E Distributions of housekeeping gene and lncRNA (F) expression levels in neocortex single cells, binned by log2(Normalized Counts + 1). Colors represent number of cells in each bin. Abundant lncRNAs were ranked by their median expression levels across 276 neocortex single cells. (PDF 257 kb)