Additional file 10: of Incorporating individual historical controls and aggregate treatment effect estimates into a Bayesian survival trial: a simulation study

Tables A7-A12. Impact of α0 and ω on the operating characteristics for scenarios S1 to S12 when σ H 2 $$ {\upsigma}_{\mathrm{H}}^2 $$ is equivalent to 66 or 22 events. These tables describe the impact of α0 and ω on the operating characteristics for scenarios S1 to S4 (Tables A7 and A10), when historical and new control arm are commensurate, for scenarios S5 to S8 (Tables A8 and A11), when there is a negative prior-data conflict, and for scenarios S9 to S12 (Tables A9 and A12), when there is a positive prior-data conflict. A Weibull distribution is used to generate and analyse historical and new data, and σ H 2 $$ {\upsigma}_{\mathrm{H}}^2 $$ is equivalent to 66 (Tables A7-A9) or 22 (Tables A10-A12) events. (PDF 689 kb)